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    文章类型: English Abstract
    背景:这项研究的目的是分析在公共和私营部门的一系列外科专业中实施增强恢复计划(ERP)的比率。
    方法:这是一项基于2019年3月至12月住院时间的回顾性纵向研究。我们研究了ERP协议中最常见的13个活动部分。选择的程序包括消化,妇科,骨科,胸廓,和泌尿外科手术。评估标准是ERP的比率。首先对结果进行总体分析,然后根据机构类型将ERP停留与非ERP停留相匹配,患者年龄和性别,出院月份,和Charlson合并症得分.
    结果:我们考虑了420,031次停留,其中78119个被编码为ERP。有62,403个非ERP停留。根据手术类型,执行率从5%到30%不等。私营部门的ERP总体实施率(21.2%)高于公共部门(14.4%)。一些手术的结果是相反的,特别是一些癌症。患者在公共部门的Charlson得分较高。
    结论:这项大规模的国家研究提供了法国ERP扩散程度的图片。尽管部门之间存在差异,这种扩散总体上仍然不够。鉴于已证明的ERP的好处,需要更多的教育努力来改善它们在法国的实施。
    BACKGROUND: The aim of this study was to analyze the rate of enhanced recovery programs (ERP) implementation in a range of surgical specialties in both the public and private sectors.
    METHODS: This was a retrospective longitudinal study based on hospital stays between March to December 2019. We studied thirteen of the activity segments most frequently included in ERP protocol. The procedures selected included digestive, gynecological, orthopedic, thoracic, and urological procedures. The assessment criteria was the rate of ERP. The results were analyzed first overall and then matching ERP stays to non-ERP stays according to type of institution, patient age and sex, month of discharge, and Charlson comorbidity score.
    RESULTS: We took 420,031 stays into account, of which 78,119 were coded as ERP. There were 62,403 non-ERP stays. Depending on the type of surgery, the implementation rate ranged from 5 percent to 30 percent. The overall rate of ERP implementation was higher in the private sector (21.2 percent) than in the public sector (14.4 percent). The results are reversed for some surgeries, notably for some cancers. Patients had a higher Charlson score in the public sector.
    CONCLUSIONS: This large-scale national study provides a picture of the degree of diffusion of ERPs in France. Although there are differences between sectors, this diffusion is still insufficient overall. Given the demonstrated benefits of ERPs, more educational efforts are needed to improve their implementation in France.
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  • 文章类型: Journal Article
    目的:胃肠功能的恢复和术后肠梗阻是粘连性小肠梗阻手术后临床医生的首要目标。虽然增强的恢复计划可以改善恢复,它们在急诊手术中的可行性尚未得到证实。我们试图评估ASBO手术后患者术后肠梗阻的发生率和强化康复计划的可行性。包括它们在恢复胃肠功能和减少住院时间方面的益处。
    方法:这项前瞻性研究包括2021年6月至2022年11月接受ASBO手术治疗的前50名患者。他们的手术是作为急诊手术或经过短期治疗后进行的。主要目的是将观察到的术后肠梗阻率与理论率进行比较,设定在40%。该研究方案在clinicaltrials.gov中注册,编号为NCT04929275。
    结果:本研究纳入的50例患者中,它报告了16%的术后肠梗阻,显著低于假设的40%(p=0.0004)。强化恢复计划的中位依从性为75%(95CI:70.1-79.9)。观察到的最低项目是TAP阻滞(26%),观察到的最高项目是术前咨询和对镇痛方案的依从性(100%)。总发病率为26.5%,但是仅在3例患者中观察到严重的发病率(Dindo-Clavien>3)(6%)。严重发病率与ERP无关。
    结论:强化康复方案在粘连性小肠梗阻手术患者中是可行和安全的,可促进胃肠功能的恢复。
    背景:NCT04929275。这项研究对该领域有什么帮助?:需要改进粘连性小肠梗阻(ASBO)手术的围手术期管理,以降低发病率。在ASBO紧急手术后,增强恢复计划(ERP)既可行又安全。ERPs可以改善胃肠道(GI)功能的恢复。
    OBJECTIVE: The recovery of gastrointestinal function and postoperative ileus are the leading goals for clinicians following surgery for adhesive small bowel obstruction. While enhanced recovery programs may improve recovery, their feasibility in emergency surgery has not yet been proven. We sought to assess the incidence of postoperative ileus in patients following surgery for ASBO and the feasibility of enhanced recovery programs, including their benefits in the recovery of gastrointestinal functions and reducing the length of hospitalization.
    METHODS: This prospective study includes the first 50 patients surgically treated for ASBO between June 2021 and November 2022. Their surgery was performed either as an emergency procedure or after a short course of medical treatment. The main aim was to compare the observed rate of postoperative ileus with a theoretical rate, set at 40%. The study protocol was registered in clinicaltrials.gov under the number NCT04929275.
    RESULTS: Among the 50 patients included in this study, it reported postoperative ileus in 16%, which is significantly lower than the hypothetical rate of 40% (p = 0.0004). The median compliance with enhanced recovery programs was 75% (95%CI: 70.1-79.9). The lowest item observed was the TAP block (26%) and the highest observed items were preoperative counselling and compliance with analgesic protocols (100%). The overall morbidity was 26.5%, but severe morbidity (Dindo-Clavien > 3) was observed in only 3 patients (6%). Severe morbidity was not related with the ERP.
    CONCLUSIONS: Enhanced recovery programs are feasible and safe in adhesive small bowel obstruction surgery patients and could improve the recovery of gastrointestinal functions.
    BACKGROUND: NCT04929275. WHAT DOES THE STUDY CONTRIBUTE TO THE FIELD?: Perioperative management of adhesive small bowel obstruction (ASBO) surgery needs to be improved in order to reduce morbidity. Enhanced recovery programs (ERP) are both feasible and safe following urgent surgery for ASBO. ERPs may improve the recovery of gastrointestinal (GI) functions.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    尚未完成对探索增强术后恢复(ERAS)指南结果的证据的全面审查。
    为了评估ERAS指南是否与改善住院时间相关,医院再入院,并发症,和死亡率与常规手术治疗相比,并了解基于研究和患者因素的估计差异。
    MEDLINE,Embase,护理和相关健康文献的累积指数,和CochraneCentral从一开始就被搜索到2021年6月。
    标题,摘要,全文由两名独立审稿人筛选。符合条件的研究是随机临床试验,与对照组相比,检查了ERAS引导的手术,并报告了至少1个结果。
    使用标准化数据抽象表单对数据进行一式两份的抽象。该研究遵循了系统评价和荟萃分析的首选报告项目。使用Cochrane偏差风险工具重复评估偏差风险。随机效应荟萃分析用于汇集每个结果的估计值,元回归确定了每个结果中异质性的来源。
    主要结果是住院时间,出院后30天内再次入院,术后30天并发症,和术后30天死亡率。
    在确定的12047个参考文献中,1493个全文进行了资格筛选,495人被纳入系统评价,和74个RCTs,9076名参与者被纳入荟萃分析.纳入的研究提供了来自21个国家和9个ERAS引导的外科手术的数据,其中15个(20.3%)具有低偏倚风险。ERAS合规性的平均值(SD)报告,结果,要素研究清单得分为13.5(2.3)。住院时间减少1.88天(95%CI,0.95-2.81天;I2=86.5%;P<.001),并发症风险降低(风险比,ERAS组0.71;95%CI,0.59-0.87;I2=78.6%;P<.001)。再入院和死亡率的风险并不显著。
    在此荟萃分析中,ERAS指南与住院时间减少和并发症相关。未来的研究应旨在改善ERAS的实施并增加指南的覆盖范围。
    UNASSIGNED: A comprehensive review of the evidence exploring the outcomes of enhanced recovery after surgery (ERAS) guidelines has not been completed.
    UNASSIGNED: To evaluate if ERAS guidelines are associated with improved hospital length of stay, hospital readmission, complications, and mortality compared with usual surgical care, and to understand differences in estimates based on study and patient factors.
    UNASSIGNED: MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, and Cochrane Central were searched from inception until June 2021.
    UNASSIGNED: Titles, abstracts, and full-text articles were screened by 2 independent reviewers. Eligible studies were randomized clinical trials that examined ERAS-guided surgery compared with a control group and reported on at least 1 of the outcomes.
    UNASSIGNED: Data were abstracted in duplicate using a standardized data abstraction form. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Risk of bias was assessed in duplicate using the Cochrane Risk of Bias tool. Random-effects meta-analysis was used to pool estimates for each outcome, and meta-regression identified sources of heterogeneity within each outcome.
    UNASSIGNED: The primary outcomes were hospital length of stay, hospital readmission within 30 days of index discharge, 30-day postoperative complications, and 30-day postoperative mortality.
    UNASSIGNED: Of the 12 047 references identified, 1493 full texts were screened for eligibility, 495 were included in the systematic review, and 74 RCTs with 9076 participants were included in the meta-analysis. Included studies presented data from 21 countries and 9 ERAS-guided surgical procedures with 15 (20.3%) having a low risk of bias. The mean (SD) Reporting on ERAS Compliance, Outcomes, and Elements Research checklist score was 13.5 (2.3). Hospital length of stay decreased by 1.88 days (95% CI, 0.95-2.81 days; I2 = 86.5%; P < .001) and the risk of complications decreased (risk ratio, 0.71; 95% CI, 0.59-0.87; I2 = 78.6%; P < .001) in the ERAS group. Risk of readmission and mortality were not significant.
    UNASSIGNED: In this meta-analysis, ERAS guidelines were associated with decreased hospital length of stay and complications. Future studies should aim to improve implementation of ERAS and increase the reach of the guidelines.
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  • 文章类型: Journal Article
    目的:手术后加速恢复(ERAS)是一个多学科,以患者为中心的方法旨在加快康复,改善临床结果,降低医疗成本。最初是为结直肠手术开发的,ERAS原则已成功应用于各种外科专业,包括心脏手术.这项研究概述了洛桑大学医院心脏血管部三级心脏外科中心ERAS计划的实施和认证过程。
    方法:实施涉及组建多学科团队,包括心脏外科医生,麻醉师,密集主义者,心脏病专家,临床护士专家,和物理治疗师。ERAS护士协调员在组织会议中发挥了核心作用,推动该计划,制定协议,和收集数据。认证过程要求遵守ERAS准则,结构化培训,和外部评估。关键阶段包括ERAS前数据收集,协议传播,纳入第一批患者,其次是分析和全面实施。
    结果:要获得认证,必须对已建立的协议保持70%以上的合规率。这个过程涉及克服各种障碍,例如不一致的做法和多学科合作的必要性。在本文中,我们为这些挑战提供了一些解决方案,包括团队教育,定期会议,和连续的反馈循环。最初队列的初步数据显示早期动员有所改善,阿片类药物的使用,呼吸系统并发症,缩短住院时间。
    结论:ERAS计划在我们机构的成功实施证明了结构化,心脏外科多学科方法。持续的自我评估和遵守指南对于持续改善患者预后和医疗保健效率至关重要。
    OBJECTIVE: Enhanced Recovery After Surgery (ERAS) is a multidisciplinary, patient-centred approach aimed at expediting recovery, improving clinical outcomes, and reducing healthcare costs. Initially developed for colorectal surgery, ERAS principles have been successfully applied across various surgical specialties, including cardiac surgery. This study outlines the implementation and certification process of the ERAS program in a tertiary cardiac surgical centre within the Heart-Vessel Department at Lausanne University Hospital.
    METHODS: The implementation involved forming a multidisciplinary team, including cardiac surgeons, anaesthesiologists, intensivists, a cardiologist, clinical nurse specialists, and physiotherapists. The ERAS nurse coordinator played a central role in organizing meetings, promoting the program, developing protocols, and collecting data. The certification process required adherence to ERAS guidelines, structured training, and external evaluation. Key phases included pre-ERAS data collection, protocol dissemination, inclusion of the first patients, followed by analysis and full implementation.
    RESULTS: Achieving certification required maintaining a compliance rate of over 70% with established protocols. The process involved overcoming various barriers, such as inconsistent practices and the need for multidisciplinary collaboration. In this paper, we provide some solutions to these challenges, including team education, regular meetings, and continuous feedback loops. Preliminary data from the initial cohort showed improvement in early mobilization, opioid use, respiratory complications, and shorter hospital stays.
    CONCLUSIONS: The successful implementation of the ERAS program at our institution demonstrates the feasibility and benefits of a structured, multidisciplinary approach in cardiac surgery. Continuous self-assessment and adherence to guidelines are essential for sustained improvement in patient outcomes and healthcare efficiency.
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  • 文章类型: Journal Article
    目的:探讨加速康复外科(ERAS)在老年肾结石手术中的应用效果。
    方法:华西医院104例老年肾结石患者的临床资料,本研究对四川大学2020年1月至2022年12月进行回顾性分析。根据不同的护理方案将患者分为两组。其中,对照组52例患者接受常规护理,研究组52例患者接受ERAS模式护理。术后恢复,焦虑,并发症,比较两组患者的应激反应和生活质量。
    结果:研究组术后康复指标恢复时间明显短于对照组(P<0.05)。研究组还表现出血尿等并发症的发生率显着降低,腹痛,呕吐,发冷,发烧,低血压(均P<0.05)。在开始护理之前,两组患者的状态焦虑量表(SAI)和特质焦虑量表(TAI)评分比较,差异均无统计学意义(均P>0.05)。然而,护理后,研究组的SAI和TAI评分均低于对照组(均P<0.05)。同样,两组护理前一般生活质量量表-74(GQOLI-74)各维度评分比较,差异均无统计学意义(P>0.05),但研究组护理后各维度得分均较高(P<0.05)。血红素氧合酶-1(HO-1)的水平,内皮素-1(ET-1),促肾上腺皮质激素(ACTH),研究组护理后皮质醇(Cor)水平明显降低(均P<0.05)。研究组患者对护理的认可度和认可评分均高于对照组(P<0.05)。
    结论:ERAS在老年肾结石患者经尿道输尿管钬激光碎石术中的应用可有效缓解应激反应。提高生活质量,减少围手术期焦虑,尽量减少并发症的发生率,促进患者整体康复。
    OBJECTIVE: To investigate the efficacy and application of Enhanced Recovery After Surgery (ERAS) in elderly patients undergoing surgery for kidney stones.
    METHODS: Clinical data of 104 elderly patients who underwent kidney stone surgery at West China Hospital, Sichuan University from January 2020 to December 2022 were retrospectively analyzed in this study. The patients were divided into two groups according to different nursing plans. Among them, 52 patients in the control group received conventional nursing, and 52 patients in the study group received ERAS mode nursing. Postoperative recovery, anxiety, complications, stress response and quality of life were compared between the two groups.
    RESULTS: The time to recovery of postoperative rehabilitation indices in the research group was significantly shorter compared to the control group (P < 0.05). The research group also exhibited a significantly lower incidence of complications such as hematuria, abdominal pain, vomiting, chills, fever, and hypotension (all P < 0.05). Before the initiation of nursing care, there were no significant differences in the State Anxiety Inventory (SAI) and Trait Anxiety Inventory (TAI) scores between the two groups (both P > 0.05). However, after nursing care, the research group exhibited lower SAI and TAI scores compared to the control group (all P < 0.05). Similarly, there was no significant difference in the General Quality of Life Inventory-74 (GQOLI-74) scores in any dimension between the two groups before nursing care (P > 0.05), but the research group showcased higher scores in every dimension after nursing care (P < 0.05). The levels of Heme Oxygenase-1 (HO-1), Endothelin-1 (ET-1), Adrenocorticotropic Hormone (ACTH), and Cortisol (Cor) were significantly lower in the research group after nursing care (all P < 0.05). The acknowledgment and approval scores of nursing care in the research group were higher than those in the control group (P < 0.05).
    CONCLUSIONS: The application of ERAS in elderly patients with kidney stones undergoing transurethral ureteral holmium laser lithotripsy is efficacious in mitigating stress reactions, enhancing quality of life and reducing perioperative anxiety, minimizing the incidence of complications, and promoting overall patient recovery.
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  • 文章类型: Journal Article
    术后肠梗阻(POI)是一种常见的手术并发症,导致住院时间延长,病人的痛苦,和巨大的经济负担。文献旨在简要概述预防和治疗POI术后的干预措施。2014年至2023年的数据来自PubMed等知名来源,PubMedCentral,谷歌学者,研究门,科学直接。纳入标准侧重于探索POI的创新治疗和预防策略的研究,使用关键词,如新型POI治疗,非药物预防,POI发病率,POI管理,和风险因素。调查结果表明,咖啡消费等预防措施的整合,口香糖,益生菌,在增强恢复计划中使用dikenchuto显着降低了POI的频率和持续时间,没有任何不良影响,微创手术方法有望作为额外的预防策略。虽然治疗方案如alvimopan,NSAIDs,和针灸已经证明了疗效,由于相关的不良反应,利多卡因的使用引起了人们的关注.不断探索新的治疗策略,如靶向肥大细胞,迷走神经刺激和紧密连接蛋白,和促动力介导的胆碱能抗炎途径的激发不仅有望增强治疗,而且加深了对POI背后复杂的细胞和分子途径的理解。POI在各种外科专业中提出了复杂的挑战,需要多方面的管理方法。在增强的恢复计划中整合预防和治疗措施显着减少了POI的频率和持续时间。
    Postoperative ileus (POI) is a prevalent surgical complication, which results in prolonged hospitalization, patient distress, and substantial economic burden. The literature aims to present a brief outline of interventions for preventing and treating POI post-surgery. Data from 2014 to 2023 were gathered from reputable sources like PubMed, PubMed Central, Google Scholar, Research Gate, and Science Direct. Inclusion criteria focused on studies exploring innovative treatments and prevention strategies for POI, using keywords such as novel POI treatments, non-pharmacological prevention, POI incidence rates, POI management, and risk factors. The findings revealed that integration of preventive measures such as coffee consumption, chewing gum, probiotics, and use of dikenchuto within enhanced recovery programs has significantly reduced both the frequency and duration of POI, without any adverse effects, with minimally invasive surgical approaches showing promise as an additional preventive strategy. While treatment options such as alvimopan, NSAIDs, and acupuncture have demonstrated efficacy, the use of lidocaine has raised concerns due to associated adverse effects. The ongoing exploration of novel therapeutic strategies such as targeting the mast cells, vagal nerve stimulation and tight junction protein, and prokinetic-mediated instigation of the cholinergic anti-inflammatory trail not only holds promise for enhanced treatment but also deepens the understanding of intricate cellular and molecular pathways underlying POI. POI presents a complex challenge in various surgical specialties, necessitating a multifaceted management approach. The integration of preventive and treatment measures within enhanced recovery programs has significantly reduced POI frequency and duration.
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  • 文章类型: Journal Article
    背景:增强术后恢复(ERAS®)是一种多模式的围手术期护理途径,旨在减轻手术压力并最终改善患者的康复和预后。它可能需要大量资源,但具有已证明的好处。这项研究的主要目的是对当地结直肠外科中心的围手术期实践进行诊断评估。
    方法:对2022年1月至12月行择期结直肠手术的93例患者进行分析。预存,术前,所有患者的术后数据都收集在研究人员开发的数据库中,根据ERAS®指南。描述性统计用于总结人口统计学和临床特征。进行卡方和T检验以确定分类变量与术后并发症之间的可能关联。
    结果:总体分析显示患者术前优化不足,特别是关于营养咨询和补充,戒烟和戒酒,贫血治疗(9%),和麻醉前药物(42%)。在术后期间和口服摄入(平均在第六天开始),侵入性装置的移除显着延迟(在第四天平均移除导尿管,在第五天平均移除手术引流)。两者都导致住院时间(平均13天)和大量并发症。
    结论:结果引导我们对当前实践和结果进行个人和多学科的反思。ERAS®计划,已经被许多中心采用,可能对丰沙尔中心医院结直肠患者的术后即刻恢复产生积极影响,实施似乎有必要。
    BACKGROUND: The enhanced recovery after surgery (ERAS®) is a multimodal perioperative care pathway designed to reduce surgical stress and ultimately improve patient recovery and outcome. It can require significant resources but with proven benefits. The main goal of this study was to perform a diagnostic assessment of perioperative practice in a local colorectal surgical center.
    METHODS: 93 patients who underwent elective colorectal surgery from January to December 2022 were analyzed. Preadmission, preoperative, and postoperative data of all patients were collected in a database developed by the researchers, according to ERAS® guidelines. Descriptive statistics were employed to summarize demographic and clinical characteristics. Chi-square and T-test were performed to identify possible associations between categorical variables and postoperative complications.
    RESULTS: Overall analysis showed deficient preoperative patient optimization, especially regarding nutritional counseling and supplementation, smoking and alcohol cessation, anemia treatment (9%), and pre-anesthetic medication (42%). Removal of invasive devices was significantly delayed (removal of urinary catheter average on the fourthday and surgical drain average on the fifth day) in the postoperatively period and oral intake (average onset on the sixth day). Both contribute to hospital length of stay (mean of 13 days) and a significant number of complications.
    CONCLUSIONS: The results lead us to an individual and multidisciplinary reflection on current practices and outcomes. ERAS® program, already adopted by many centers, could have a positive impact on the immediate postoperative recovery of colorectal patients in Funchal Central Hospital and implementation seems necessary.
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